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10 Best Cough And Congestion Medicine of 2026
Last updated on 05/20/2026
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1
Mucinex DM 12Hr Maximum Strength Chest Congestion & Cough Medicine for Adults, Cold and Cough Medicine for Excess Mucus Relief, 1200 mg Guaifenesin & 60 mg Dextromethorphan HBr, 48 Bi-Layer Tablets
Mucinex
Why we love it
Powerful cough and cold relief.
Long-lasting symptom control.
Trusted quality and effectiveness.
Main Highlights
COUGH & COLD MEDICINE FOR ADULTS: Maximum Strength Mucinex DM 12-hour expectorant & cough suppressant packs a powerful punch with 60 mg dextromethorphan HBr & 1200 mg guaifenesin extended release tablets
EXCESS MUCUS RELIEF: Maximum Strength Mucinex DM 12hr provides powerful relief for your chest congestion & cough & lasts up to 12 hours; this cough suppressant for adults gives much needed relief from bothersome symptoms
EXPECTORANT FOR ADULTS: Maximum Strength Mucinex DM cough medicine for adults helps thin and loosen mucus for easier expectoration; Say goodbye to chest congestion and cough, say hello to excess mucus relief with our original bi-layer tablets
EXTENDED RELEASE GUAIFENESIN & DEXTROMETHORPHAN HBr: Experience long-lasting symptom relief with Maximum Strength Mucinex DM 12 hr extended-release 1200 mg guaifenesin and 60 mg dextromethorphan HBr tablets
COLD AND FLU MEDICINE FOR ADULTS: For powerful cough, cold, and flu multi-symptom relief, check out our range of Mucinex Fast-Max nighttime cold and flu & daytime cold and flu medicines; Beat cold and flu symptoms with confidence
USAGE: Use as directed; For ages 12+ years
QUALITY YOU CAN TRUST: Mucinex uses carbomer that is manufactured without the use of benzene
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9.7
Exceptional
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9.7
Exceptional
Mucinex
Mucinex DM 12Hr Maximum Strength Chest Congestion & Cough Medicine for Adults, Cold and Cough Medicine for Excess Mucus Relief, 1200 mg Guaifenesin & 60 mg Dextromethorphan HBr, 48 Bi-Layer Tablets
Check Price
Show More
Why we love it
Powerful cough and cold relief.
Long-lasting symptom control.
Trusted quality and effectiveness.
Main Highlights
COUGH & COLD MEDICINE FOR ADULTS: Maximum Strength Mucinex DM 12-hour expectorant & cough suppressant packs a powerful punch with 60 mg dextromethorphan HBr & 1200 mg guaifenesin extended release tablets
EXCESS MUCUS RELIEF: Maximum Strength Mucinex DM 12hr provides powerful relief for your chest congestion & cough & lasts up to 12 hours; this cough suppressant for adults gives much needed relief from bothersome symptoms
EXPECTORANT FOR ADULTS: Maximum Strength Mucinex DM cough medicine for adults helps thin and loosen mucus for easier expectoration; Say goodbye to chest congestion and cough, say hello to excess mucus relief with our original bi-layer tablets
EXTENDED RELEASE GUAIFENESIN & DEXTROMETHORPHAN HBr: Experience long-lasting symptom relief with Maximum Strength Mucinex DM 12 hr extended-release 1200 mg guaifenesin and 60 mg dextromethorphan HBr tablets
COLD AND FLU MEDICINE FOR ADULTS: For powerful cough, cold, and flu multi-symptom relief, check out our range of Mucinex Fast-Max nighttime cold and flu & daytime cold and flu medicines; Beat cold and flu symptoms with confidence
USAGE: Use as directed; For ages 12+ years
QUALITY YOU CAN TRUST: Mucinex uses carbomer that is manufactured without the use of benzene
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Value for Money
2
Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Cough Suppressant and Expectorant, Raspberry Flavor, 8 Fl Oz x 2
Robitussin
Why we love it
Fast relief from coughs.
Effective chest congestion support.
Raspberry flavor for daytime use.
Main Highlights
Two 8 fl oz bottles of Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Cough Suppressant and Expectorant, Raspberry Flavor
Relief for cough and an expectorant for relief of chest congestion
Maximum-strength cough relief formula with expectorant that thins and loosens mucus for productive coughs
Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
Cough suppressant and liquid expectorant suitable for adults and children 12 years and over
HSA and FSA eligible product
Show More
9.6
Superb
Check Price
9.6
Superb
Robitussin
Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Cough Suppressant and Expectorant, Raspberry Flavor, 8 Fl Oz x 2
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Why we love it
Fast relief from coughs.
Effective chest congestion support.
Raspberry flavor for daytime use.
Main Highlights
Two 8 fl oz bottles of Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Cough Suppressant and Expectorant, Raspberry Flavor
Relief for cough and an expectorant for relief of chest congestion
Maximum-strength cough relief formula with expectorant that thins and loosens mucus for productive coughs
Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
Cough suppressant and liquid expectorant suitable for adults and children 12 years and over
HSA and FSA eligible product
Show More
3
Mucinex Fast-Max & NightShift Combo Pack - Max Strength Cough & Cold Medicines For Mucus Relief, Chest Congestion, Nasal Congestion, Sinus Congestion, Sinus Pressure, Cough Symptom Relief (2x 6 FL OZ)
Mucinex
5% Off
Why we love it
Powerful multi-symptom relief.
Triple action formula works effectively.
Trusted brand doctors recommend.
Main Highlights
COUGH COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast Max Severe Congestion & Cough and NightShift Cold & Flu provides powerful multi-symptom relief for your worst symptoms
EXPECTORANT & DECONGESTANTS FOR ADULTS: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough has a Triple Action Formula that helps to relieve nasal & chest congestion, control cough & helps thin & loosen mucus to make coughs more productive
NIGHTTIME COLD AND FLU SYMPTOM RELIEF: Mucinex Nightshift Cold & Flu helps to reduce fever, relieve headache, minor aches and pains, sore throat, coughing, sneezing, & runny nose for a better morning
MUCINEX FAST-MAX SEVERE CONGESTION & COUGH ACTIVE INGREDIENTS: Dextromethorphan HBr - Cough suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal decongestant
MUCINEX NIGHTSHIFT COLD & FLU ACTIVE INGREDIENTS: Contains Acetaminophen - Pain reliever and fever reducer; Dextromethorphan HBr - Cough suppressant; Triprolidine HCl – Antihistamine
USAGE: Use as directed; For ages 12+ years
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9.5
Superb
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9.5
Superb
Mucinex
Mucinex Fast-Max & NightShift Combo Pack - Max Strength Cough & Cold Medicines For Mucus Relief, Chest Congestion, Nasal Congestion, Sinus Congestion, Sinus Pressure, Cough Symptom Relief (2x 6 FL OZ)
5% Off
Check Price
Show More
Why we love it
Powerful multi-symptom relief.
Triple action formula works effectively.
Trusted brand doctors recommend.
Main Highlights
COUGH COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast Max Severe Congestion & Cough and NightShift Cold & Flu provides powerful multi-symptom relief for your worst symptoms
EXPECTORANT & DECONGESTANTS FOR ADULTS: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough has a Triple Action Formula that helps to relieve nasal & chest congestion, control cough & helps thin & loosen mucus to make coughs more productive
NIGHTTIME COLD AND FLU SYMPTOM RELIEF: Mucinex Nightshift Cold & Flu helps to reduce fever, relieve headache, minor aches and pains, sore throat, coughing, sneezing, & runny nose for a better morning
MUCINEX FAST-MAX SEVERE CONGESTION & COUGH ACTIVE INGREDIENTS: Dextromethorphan HBr - Cough suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal decongestant
MUCINEX NIGHTSHIFT COLD & FLU ACTIVE INGREDIENTS: Contains Acetaminophen - Pain reliever and fever reducer; Dextromethorphan HBr - Cough suppressant; Triprolidine HCl – Antihistamine
USAGE: Use as directed; For ages 12+ years
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4
Mucinex Fast-Max Severe Congestion & Cough Medicine for Adults, Cough & Bothersome Mucus Relief with Dextromethorphan HBr & Guaifenesin, Cough Suppressant & Expectorant Medicine, 20 Count
Mucinex
7% Off
Why we love it
Powerful relief for cold symptoms.
Effective cough suppression included.
Mucus thinning for easier breathing.
Main Highlights
COLD MEDICINE FOR ADULTS: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough caplets provide powerful multi-symptom relief for your worst cold and cough symptoms
OVER-THE-COUNTER MEDICATION: Mucinex caplets contain active ingredients to help you feel better; Dextromethorphan HBr is a cough suppressant and Guaifenesin is an expectorant; Use as directed; For ages 12+
COUGH MEDICINE: Contains Dextromethorphan HBr, a cough suppressant, to help reduce the urge to cough
MUCUS RELIEF: The expectorant, Guaifenesin, provides mucus relief by thinning and loosening bothersome mucus in your chest, helping to clear chest congestion
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9.4
Superb
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9.4
Superb
Mucinex
Mucinex Fast-Max Severe Congestion & Cough Medicine for Adults, Cough & Bothersome Mucus Relief with Dextromethorphan HBr & Guaifenesin, Cough Suppressant & Expectorant Medicine, 20 Count
7% Off
Check Price
Show More
Why we love it
Powerful relief for cold symptoms.
Effective cough suppression included.
Mucus thinning for easier breathing.
Main Highlights
COLD MEDICINE FOR ADULTS: Maximum Strength Mucinex Fast-Max Severe Congestion & Cough caplets provide powerful multi-symptom relief for your worst cold and cough symptoms
OVER-THE-COUNTER MEDICATION: Mucinex caplets contain active ingredients to help you feel better; Dextromethorphan HBr is a cough suppressant and Guaifenesin is an expectorant; Use as directed; For ages 12+
COUGH MEDICINE: Contains Dextromethorphan HBr, a cough suppressant, to help reduce the urge to cough
MUCUS RELIEF: The expectorant, Guaifenesin, provides mucus relief by thinning and loosening bothersome mucus in your chest, helping to clear chest congestion
Show More
5
Mucinex Fast-Max Severe Congestion & Cough Medicine, Maximum Strength Symptom Relief, Over-The-Counter Medication, Cold Medicine, Cough Suppressant, Expectorant, Nasal Decongestant, 6 FL OZ
Mucinex
22% Off
Why we love it
Rapid multi-symptom relief.
Trusted by doctors and pharmacists.
Thins mucus for easier breathing.
Main Highlights
COUGH COLD AND FLU MEDICINES FOR ADULTS: Maximum Strength Mucinex Fast Max Severe Congestion & Cough provides powerful multi-symptom relief for your worst symptoms including cough, chest congestion, and nasal congestion
EXPECTORANTS AND DECONGESTANTS FOR ADULTS : Maximum Strength Mucinex Fast-Max Severe Congestion & Cough has a triple action formula that relieves nasal & chest congestion, controls cough & thins & loosens mucus to help clear lungs of excess mucus
POWERFUL COUGH & COLD ACTIVE INGREDIENTS: Contains Dextromethorphan HBr - Cough suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal decongestant
USAGE: Use as directed; For ages 12+ years
Show More
9.3
Superb
Check Price
9.3
Superb
Mucinex
Mucinex Fast-Max Severe Congestion & Cough Medicine, Maximum Strength Symptom Relief, Over-The-Counter Medication, Cold Medicine, Cough Suppressant, Expectorant, Nasal Decongestant, 6 FL OZ
22% Off
Check Price
Show More
Why we love it
Rapid multi-symptom relief.
Trusted by doctors and pharmacists.
Thins mucus for easier breathing.
Main Highlights
COUGH COLD AND FLU MEDICINES FOR ADULTS: Maximum Strength Mucinex Fast Max Severe Congestion & Cough provides powerful multi-symptom relief for your worst symptoms including cough, chest congestion, and nasal congestion
EXPECTORANTS AND DECONGESTANTS FOR ADULTS : Maximum Strength Mucinex Fast-Max Severe Congestion & Cough has a triple action formula that relieves nasal & chest congestion, controls cough & thins & loosens mucus to help clear lungs of excess mucus
POWERFUL COUGH & COLD ACTIVE INGREDIENTS: Contains Dextromethorphan HBr - Cough suppressant; Guaifenesin - Expectorant; Phenylephrine HCI - Nasal decongestant
USAGE: Use as directed; For ages 12+ years
Show More
6
Robitussin Adult Maximum Strength Cough + Chest Congestion DM Max (8 fl. oz. Bottle), Cough Suppressant & Expectorant, Raspberry Flavor
Robitussin
Why we love it
Tackles mucus for effective relief.
Raspberry flavor makes it enjoyable.
Safe for adults and kids.
Main Highlights
One 8 fl oz bottle of Robitussin Maximum Strength Cough and Chest Congestion DM Liquid, Congestion Relief and Cough Medicine, Raspberry Flavor
Robitussin recently conducted a First of Its Kind Real‑World Evidence study showing that Robitussin DM Max helps provide fast, powerful cough relief that gets you back to everyday life from Day 1.
Cough suppressant for relief for cough and an expectorant for relief of chest congestion
Maximum-strength formula with expectorant that thins and loosens mucus for productive coughs
Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
Suitable for adults and children 12 years and over
Take 20 mL by mouth every four hours while symptoms persist
HSA and FSA eligible product
Show More
9.3
Superb
Check Price
9.3
Superb
Robitussin
Robitussin Adult Maximum Strength Cough + Chest Congestion DM Max (8 fl. oz. Bottle), Cough Suppressant & Expectorant, Raspberry Flavor
Check Price
Show More
Why we love it
Tackles mucus for effective relief.
Raspberry flavor makes it enjoyable.
Safe for adults and kids.
Main Highlights
One 8 fl oz bottle of Robitussin Maximum Strength Cough and Chest Congestion DM Liquid, Congestion Relief and Cough Medicine, Raspberry Flavor
Robitussin recently conducted a First of Its Kind Real‑World Evidence study showing that Robitussin DM Max helps provide fast, powerful cough relief that gets you back to everyday life from Day 1.
Cough suppressant for relief for cough and an expectorant for relief of chest congestion
Maximum-strength formula with expectorant that thins and loosens mucus for productive coughs
Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
Suitable for adults and children 12 years and over
Take 20 mL by mouth every four hours while symptoms persist
HSA and FSA eligible product
Show More
7
Amazon Basic Care Mucus Relief DM, 12 Hour Chest Congestion & Cough Relief, Guaifenesin & Dextromethorphan Extended-Release Tablets, 600 mg/30 mg, 40 Count (Pack of 1) (Packaging may vary)
Amazon Basic Care
26% Off
Limited time deal
Why we love it
Effective 12-hour cough relief.
Loosens mucus for easier breathing.
Gluten-free and safe for use.
Main Highlights
ACTIVE INGREDIENTS: Contains Dextromethorphan HBr 30 mg (cough suppressant) and Guaifenesin 600 mg (expectorant), compare to the active ingredients in Mucinex DM
12 HOUR RELIEF: Provides up to 12 hours of chest congestion relief; gluten-free expectorant and cough suppressant formula
EXPECTORANT: Helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
COUGH SUPPRESSANT: Temporarily relieves cough due to minor throat and bronchial irritation from common cold or inhaled irritants; controls the impulse to cough to help you get to sleep
EFFECTIVE FORMULA: Cough suppressant and expectorant that helps thin and loosen mucus while controlling wet and dry coughs; temporarily relieves the intensity of coughing
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9.1
Superb
Check Price
9.1
Superb
Amazon Basic Care
Amazon Basic Care Mucus Relief DM, 12 Hour Chest Congestion & Cough Relief, Guaifenesin & Dextromethorphan Extended-Release Tablets, 600 mg/30 mg, 40 Count (Pack of 1) (Packaging may vary)
26% Off
Limited time deal
Check Price
Show More
Why we love it
Effective 12-hour cough relief.
Loosens mucus for easier breathing.
Gluten-free and safe for use.
Main Highlights
ACTIVE INGREDIENTS: Contains Dextromethorphan HBr 30 mg (cough suppressant) and Guaifenesin 600 mg (expectorant), compare to the active ingredients in Mucinex DM
12 HOUR RELIEF: Provides up to 12 hours of chest congestion relief; gluten-free expectorant and cough suppressant formula
EXPECTORANT: Helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
COUGH SUPPRESSANT: Temporarily relieves cough due to minor throat and bronchial irritation from common cold or inhaled irritants; controls the impulse to cough to help you get to sleep
EFFECTIVE FORMULA: Cough suppressant and expectorant that helps thin and loosen mucus while controlling wet and dry coughs; temporarily relieves the intensity of coughing
Show More
8
Boiron Chestal Pellets for Cough and Mucus Relief, Nasal or Chest Congestion, and Sore Throat Relief - 2 Count (160 Pellets)
Boiron
25% Off
Why we love it
Portable relief for busy lives.
Dissolves easily without water.
Natural, non-drowsy formula.
Main Highlights
ON-THE-GO COUGH & MUCUS RELIEF: Chestal Cough & Mucus Pellets relieve dry coughs and minor throat irritations that can occur with a cold, and also loosen mucus to make coughs more productive.* Ideal for busy people on the move, these pellets in compact and portable tubes are convenient to take at home or on the go.
CONVENIENT MELTAWAY PELLETS: Get cough relief anywhere, anytime. Chestal Cough & Mucus Pellets dissolve easily in the mouth without water, chewing, or swallowing.
HELP YOUR FAMILY THE NATURAL WAY: This homeopathic cough and cold medicine is non-drowsy and can be taken day or night. It has no known interactions with other medications, herbs, or supplements and contains no artificial sweeteners, flavors, colors, or preservatives.
A TRUSTED BRAND: With more than 90 years of expertise, Boiron medicines are manufactured to meet the highest standards of cGMP and HPUS for purity and quality.
BUY WITH YOUR HSA/FSA: Many of your favorite Boiron medicines are now eligible for reimbursement. Look for our logo designating products that can be paid for with your Health Savings Account or Flexible Savings Account.
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8.9
Excellent
Check Price
8.9
Excellent
Boiron
Boiron Chestal Pellets for Cough and Mucus Relief, Nasal or Chest Congestion, and Sore Throat Relief - 2 Count (160 Pellets)
25% Off
Check Price
Show More
Why we love it
Portable relief for busy lives.
Dissolves easily without water.
Natural, non-drowsy formula.
Main Highlights
ON-THE-GO COUGH & MUCUS RELIEF: Chestal Cough & Mucus Pellets relieve dry coughs and minor throat irritations that can occur with a cold, and also loosen mucus to make coughs more productive.* Ideal for busy people on the move, these pellets in compact and portable tubes are convenient to take at home or on the go.
CONVENIENT MELTAWAY PELLETS: Get cough relief anywhere, anytime. Chestal Cough & Mucus Pellets dissolve easily in the mouth without water, chewing, or swallowing.
HELP YOUR FAMILY THE NATURAL WAY: This homeopathic cough and cold medicine is non-drowsy and can be taken day or night. It has no known interactions with other medications, herbs, or supplements and contains no artificial sweeteners, flavors, colors, or preservatives.
A TRUSTED BRAND: With more than 90 years of expertise, Boiron medicines are manufactured to meet the highest standards of cGMP and HPUS for purity and quality.
BUY WITH YOUR HSA/FSA: Many of your favorite Boiron medicines are now eligible for reimbursement. Look for our logo designating products that can be paid for with your Health Savings Account or Flexible Savings Account.
Show More
9
Delsym Max Strength Cough + Chest Congestion DM Liquid, Cold Medicine for Adults Relieves Cough & Chest Congestion, Expectorant Thins & Loosens Mucus, Cherry Flavor, 6 Fl Oz
Delsym
11% Off
Why we love it
Effective cough relief formula.
Powerful chest congestion support.
Great-tasting cherry flavor.
Main Highlights
COUGH SUPPRESSANT: This cough medicine for adults provides relief from cough with Dextromethorphan HBr, helping you go about your day or get to sleep at night
EXPECTORANT FOR ADULTS: Guaifenesin, an expectorant, provides powerful chest congestion relief
LOOSENS MUCUS: Breaks up mucus and thins bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
COUGH & COLD MEDICINE FOR ADULTS: Fast release cough syrup in a great-tasting cherry flavor
Use as directed, for adults and children 12 years and over
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8.8
Excellent
Check Price
8.8
Excellent
Delsym
Delsym Max Strength Cough + Chest Congestion DM Liquid, Cold Medicine for Adults Relieves Cough & Chest Congestion, Expectorant Thins & Loosens Mucus, Cherry Flavor, 6 Fl Oz
11% Off
Check Price
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Why we love it
Effective cough relief formula.
Powerful chest congestion support.
Great-tasting cherry flavor.
Main Highlights
COUGH SUPPRESSANT: This cough medicine for adults provides relief from cough with Dextromethorphan HBr, helping you go about your day or get to sleep at night
EXPECTORANT FOR ADULTS: Guaifenesin, an expectorant, provides powerful chest congestion relief
LOOSENS MUCUS: Breaks up mucus and thins bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
COUGH & COLD MEDICINE FOR ADULTS: Fast release cough syrup in a great-tasting cherry flavor
Use as directed, for adults and children 12 years and over
Show More
10
Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor - 8 Fl Oz Bottle
Robitussin
Why we love it
Fast-acting relief from cough.
Pleasant raspberry flavor enhances taste.
Easy to measure and administer.
Main Highlights
One 8 fluid ounce bottle of Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor
Cough medicine that controls and relieves frequent cough, plus thins mucus to relieve chest congestion
Liquid cough expectorant that's easy to measure and administer
Raspberry flavored cough and chest congestion expectorant provides fast relief
Cough suppressant relieves symptoms without slowing you down
Take 20 mL of Robitussin expectorant every four hours as needed
Formulated for adults and children 12 years and older
HSA and FSA eligible product
Show More
8.7
Excellent
Check Price
8.7
Excellent
Robitussin
Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor - 8 Fl Oz Bottle
Check Price
Show More
Why we love it
Fast-acting relief from cough.
Pleasant raspberry flavor enhances taste.
Easy to measure and administer.
Main Highlights
One 8 fluid ounce bottle of Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor
Cough medicine that controls and relieves frequent cough, plus thins mucus to relieve chest congestion
Liquid cough expectorant that's easy to measure and administer
Raspberry flavored cough and chest congestion expectorant provides fast relief
Cough suppressant relieves symptoms without slowing you down
Take 20 mL of Robitussin expectorant every four hours as needed
Formulated for adults and children 12 years and older
HSA and FSA eligible product
Show More